Protocols · Skin & Anti-Aging · SNAP-8
Cosmetic Ingredient · Educational

SNAP-8
Topical Reference

A reference for acetyl octapeptide-3 as a cosmetic ingredient: typical formulation concentrations and application patterns, with every figure sourced to the cited protocol guide. This is not an injectable protocol.

SNAP-8
SNAP-8 · 10 mg · cosmetic raw material
Route
Topical only
Active concentration
0.0015–0.005% w/w
Application
2×/day, periocular
Classification
Cosmetic, not a drug
Concentration

Concentration & Application

Not an injectable protocol. SNAP-8 is a topical cosmetic peptide ingredient, not an FDA-approved drug and not a compound intended for reconstitution and injection. There is no U-100 syringe dosing chart for SNAP-8 on this page because the source does not describe one; concentration is a cosmetic-formulation figure, not a personal dose. [1]

Topical formulations examined in the source use approximately 0.0015% to 0.005% active SNAP-8 by weight in the finished cream or serum. [2] Application is around the eye area (periocular skin) only. [2]

Study contextFrequencyDuration
Manufacturer testingTwice daily (morning and evening)28 days
Multi-ingredient serum studiesMorning and eveningUp to 12 weeks

Because SNAP-8 is a cosmetic ingredient rather than a therapeutic protocol, the source does not describe an on/off cycling pattern; twice-daily application is continuous for the study duration. [2]

Prep

Formulation Math

SNAP-8 vials are supplied as lyophilized powder for incorporation into a cosmetic vehicle (for example glycerin, hyaluronic acid solution, or a lightweight serum base), not for reconstitution with bacteriostatic water and injection. [2]

The source gives one documented example of formulation math: a 10 mg SNAP-8 vial incorporated into a 200 g batch yields 0.005% w/w (50 ppm) active peptide, using the formula active percent w/w = peptide (mg) ÷ final batch (g) ÷ 10. [2] Preparing a batch like this requires a calibrated analytical balance for accurate measurement; the source frames this as formulation-chemistry context, explicitly not personal dosing advice. [1][2]

Storage: follow the vial supplier's own lot-specific documentation before formulation; the source does not give a single fixed storage temperature for the unformulated vial. [2] Separately, an analytical standard of SNAP-8 remained stable for 96 hours at 4 °C in testing; the source is explicit that this does not equal the shelf life of a finished cosmetic product, and no finished-product shelf life is stated. [2]

Mechanism

How It Works

SNAP-8 is a synthetic octapeptide (an eight-amino-acid chain) with an acetyl group at the N-terminus, chemically designated acetyl octapeptide-3. [1] It is a topical cosmetic peptide ingredient used in skincare, marketed for anti-aging and wrinkle-reduction applications around the eye area; it is not an FDA-approved pharmaceutical drug and carries no approved therapeutic indication. [1]

The molecular weight and complete amino acid sequence of SNAP-8 are not explicitly stated in the sources reviewed for this page. [1] No peer-reviewed PubMed citation on SNAP-8's cosmetic efficacy, stability, or dermatological safety was available in the sources used to compile this page; the two sources cited below are both from the vial-protocol publisher, not independent journal literature. This page makes no claim of wrinkle reduction or anti-aging efficacy beyond what those two sources state about formulation concentration and study context.

SNAP-8 is not FDA-regulated as a drug, and dosage information for it should be read as topical concentration and study/formulation context, not as a personal cosmetic-use recommendation. [1][2]

Evidence

References

Only two source pages were available for SNAP-8 in the material reviewed for this page; no independently verifiable PubMed literature was found.

[1] SNAP-8 overview · PeptideDosages

[2] SNAP-8 10 mg vial dosage protocol · PeptideDosages

Educational use only. This content is for research and educational purposes only. SNAP-8 is a cosmetic ingredient, not a pharmaceutical, and this page makes no therapeutic claim. Frequency data and the full amino acid sequence were not available in the sources reviewed for this page. It is not intended for injection or ingestion.